diff --git a/docs/CHANGELOG.txt b/docs/CHANGELOG.txt
index de54242..d69fb9e 100644
--- a/docs/CHANGELOG.txt
+++ b/docs/CHANGELOG.txt
@@ -41,6 +41,7 @@
 
 - Scrolling: Fix scroll tracking with e.g. SetScrollHereX/Y() when WindowPadding < ItemSpacing.
 - Scrolling: Fix scroll snapping on edge of scroll region when both scrollbars are enabled.
+- Scrolling: Fix mouse wheel axis swap when using SHIFT on macOS (system already does it). (#4010)
 - Window: Fix IsWindowAppearing() from returning true twice in most cases. (#3982, #1497, #1061)
 - Tables: Expose TableSetColumnEnabled() in public api. (#3935)
 - TabBar: Fixed mouse reordering with very fast movements (e.g. crossing multiple tabs in a single
diff --git a/imgui.cpp b/imgui.cpp
index 67193e1..dce61e8 100644
--- a/imgui.cpp
+++ b/imgui.cpp
@@ -3738,10 +3738,17 @@
 
     // Mouse wheel scrolling
     // If a child window has the ImGuiWindowFlags_NoScrollWithMouse flag, we give a chance to scroll its parent
+    if (g.IO.KeyCtrl)
+        return;
+
+    // As a standard behavior holding SHIFT while using Vertical Mouse Wheel triggers Horizontal scroll instead
+    // (we avoid doing it on OSX as it the OS input layer handles this already)
+    const bool swap_axis = g.IO.KeyShift && !g.IO.ConfigMacOSXBehaviors;
+    const float wheel_y = swap_axis ? 0.0f : g.IO.MouseWheel;
+    const float wheel_x = swap_axis ? g.IO.MouseWheel : g.IO.MouseWheelH;
 
     // Vertical Mouse Wheel scrolling
-    const float wheel_y = (g.IO.MouseWheel != 0.0f && !g.IO.KeyShift) ? g.IO.MouseWheel : 0.0f;
-    if (wheel_y != 0.0f && !g.IO.KeyCtrl)
+    if (wheel_y != 0.0f)
     {
         StartLockWheelingWindow(window);
         while ((window->Flags & ImGuiWindowFlags_ChildWindow) && ((window->ScrollMax.y == 0.0f) || ((window->Flags & ImGuiWindowFlags_NoScrollWithMouse) && !(window->Flags & ImGuiWindowFlags_NoMouseInputs))))
@@ -3755,8 +3762,7 @@
     }
 
     // Horizontal Mouse Wheel scrolling, or Vertical Mouse Wheel w/ Shift held
-    const float wheel_x = (g.IO.MouseWheelH != 0.0f && !g.IO.KeyShift) ? g.IO.MouseWheelH : (g.IO.MouseWheel != 0.0f && g.IO.KeyShift) ? g.IO.MouseWheel : 0.0f;
-    if (wheel_x != 0.0f && !g.IO.KeyCtrl)
+    if (wheel_x != 0.0f)
     {
         StartLockWheelingWindow(window);
         while ((window->Flags & ImGuiWindowFlags_ChildWindow) && ((window->ScrollMax.x == 0.0f) || ((window->Flags & ImGuiWindowFlags_NoScrollWithMouse) && !(window->Flags & ImGuiWindowFlags_NoMouseInputs))))